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Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH et al

Sugihara, H

Novo Nordisk is testing an IL6 inhibitor, Ziltivekimab, which cut hsCRP levels by ~80-90% in the phase 2 trial: The phase 3 trial is measuring the hard outcomes: cardiovascular death, myocardial infarction, or stroke, in people with established cardiovascular disease, chronic kidney disease, and persistent inflammation

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In my opinion, this is a miserable return on investment given the billions invested and decades spent chasing tails on the wrong hypotheses