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At low concentrations, H 2 O 2 promoted cell proliferation, whereas at high concentration progressively decreased cell vitality and cell proliferation

For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)

In high doses, it is specifically toxic to the liver and generally causes liver necrosis, renal injury, or death in humans and laboratory animals 1, 2

While it is not contagious, severe cases can result in significant hair loss

Environ Sci Pollut Res 29:57625770

10.1016/J.ETAP.2005.07.015 70 LeeM