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While preclinical results are promising, clinical trials reveal considerable variability, highlighting the need for personalized approaches and robust biomarkers

He et al., 2024)

Patient safety is a top priority for Novo Nordisk, Novo Nordisk adds

It has been established that cerebral ischemic injury results in a core of necrotic tissue surrounded by a penumbra of tissue in which neurons are functionally inactive but still potentially viable [9]

Mourzano Monturo, something like that

(2023) also observed this dose- and time-dependent relationship, demonstrating that physiological adaptation occurs progressively during treatment, reducing the intensity and frequency of adverse effects after the second month of use