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Phentermine primarily works through central appetite suppression via norepinephrine release, while tirzepatide operates through incretin-based pathways affecting both peripheral and central appetite regulation, glucose metabolism, and gastric motility

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Several notable studies have examined chromium picolinate supplementation at higher doses between 600-1000mcg daily, finding it may influence hunger and food cravings

Tenrio, S., Graciliano, N

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