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Direct head-to-head data against tirzepatide showed CagriSema underperforming the highest tirzepatide dose at 84 weeks meaning monotherapy claims of comparable efficacy are not supported by current Phase 3 evidence

Walker ME, O'Donnell AA, Himali JJ, et al

Semaglutide is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management

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[16] [19] Subsequent analysis of SUSTAIN-6 data revealed that the increased risk was concentrated among patients who entered the trial with pre-existing diabetic retinopathy and experienced rapid improvements in glycemic control

When filmmaker Laura Nixs elderly cat had an intestinal blockage, her vet suggested a B12 injection along with an enema