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Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice. STAR protocols vol

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Therefore, impairment of the insulin signaling pathway (PI3K/Akt/mTOR pathway) leads to IR, which may induce the synthesis and deposition of advanced glycation end products (AGEs), ROS, and reactive nitrogen species

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dop-6 is expressed in RIC neurons 35,73 , and previous studies showed that dop-6 can inhibit RIC activity 72

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