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95% CI: -1.41 to -0.74) while reducing heterogeneity to moderate levels (I = 40.7%)

doi: 10.1371/journal.pone.0038380

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These drugs, widely used for weight loss and diabetes management, were associated with cognitive and behavioral health benefits, including reduced risks of addiction, dementia, and neurocognitive disorders

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At the pathophysiological level, obesity is characterized not only by excessive adipose tissue accumulation but also by a state of chronic low-grade inflammation directly driven by weight excess and adipose tissue expansion (Figure 1