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Similarly, TAR DNA-binding protein-43 (TDP-43) forms cytoplasmic inclusions, which are a hallmark pathology observed in sporadic ALS patients, in cultured neurons subjected to GSH depletion [18]

In aggregate, 8 regions of concern were identified from 14 of the 15 monoallelic cell lines

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Sci Rep 16 , 10196 (2026)