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Multi-center clinical comparison of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and ABM in human periodontal osseous defects

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In a clinical trial where neither the participants nor the researchers knew who received the actual drug or a fake pill (placebo), 314492 adults who were overweight or obese (with an average body mass index of 36.2) were randomly assigned to take either lorcaserin (10 mg) or placebo twice a day for 52 weeks