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If your vial has been left at room temperature for an extended period, the effective life may be shorter

Follow-up for outcomes commenced 1 month after the index date and continued until the occurrence of the outcome event, the last clinical encounter, death, or 1 year postindex date, whichever came first

Possible mechanisms for the increased ADMA concentrations include the involvement of the methionine-homocysteine pathway in the biosynthesis of ADMA and the homocysteine-mediated inhibition of ADMA metabolism by the enzyme DDAH [21], [22]

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If you experience any suspected side effects from your medication, report them to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

The Journal of biological chemistry