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The largest one is a phase 3, double-blind trial, by Novo Nordisk, aspiring to recruit 1,200 patients with NASH, with or without DM2, expected to be completed in 2028 (NCT04822181)

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Preliminary findings also suggest improvement in symptoms of chronic fatigue syndrome (22) and physical performance in patients undergoing dialysis for end-stage renal disease (9) , but data on benefits against fatigue associated with multiple sclerosis are inconclusive (21)

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