The biggest problem B12 deficient patients face once theyve achieved a diagnosis is desperate under treatment
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Collectively, these peptide-related impurities may include amino acid insertions or duplications, amino acid deletions, truncation of the N- or C-terminus, incorporation of D-stereoisomers, or amino acid side chain modifications (including deamidation, oxidation, reduction, or incomplete removal of protecting groups)
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Metabolic functions of the human gut microbiota: the role of metalloenzymes