It acknowledges that off-label use in younger patients occurs in clinical practice, but says such decisions demand careful provider assessment of risk and benefit, family history and metabolic status
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[2] [5] The pharmacological rationale behind this triple agonism is to engage complementary metabolic pathways simultaneously
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According to the authors, the findings provide an initial experimental framework for further investigation into how triple GIP/GLP-1/GCG receptor agonists may interact with brain-related pathways under diabetic conditions
