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352 A variety of studies suggest that proinflammatory factors such as IL-1, TNF , and IL-6 may contribute to DR pathogenesis

These effects make it a promising candidate for future studies on complex wound healing scenarios

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Over the past several decades, the efficacy of GHK and GHK-Cu in promoting tissue remodelling, exhibiting anti-inflammatory properties, and demonstrating antioxidant effects has been robustly validated across diverse tissues, encompassing the skin (Pickart et al., 2015), airways (Zhang et al., 2023), bones (Zhang et al., 2022)