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As I explained in my last video, chlorogenic acid, the main antioxidant in coffee, enhances autophagy in human cells, which may explain why coffee is linked to a longer life

Passwater: Ive always called GSH the foot-soldier of our antioxidant defenses

Surks MI, Sievert R

J Diabetes Sci Technol Advance Access published on Mar 11, 2024, doi: 10.1177/19322968241231565

A disrupted barrier can result from over-cleansing, using harsh skincare products, nutritional deficiencies (especially in zinc, vitamin A, and omega-3 fatty acids), and gut imbalances

In addition, higher levels of phosphorylated (active) LKB1 were noted under these conditions in the livers of KO mice but not WT mice (Fig