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Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials

Protein shakes and other concentrated sources can supplement whole food intake when appetite limits meal size

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Who should choose each option Second Nature may suit you if: You want medication and behavioural support from a single provider You want 1-to-1 coaching from HCPC or AfN-registered dietitians and nutritionists Published, peer-reviewed clinical outcomes are important to you You prefer a nutrition approach without points or calorie counting You want a provider with current NHS weight management partnerships WeightWatchers may suit you if: You already have a GLP-1 prescription and want to add structured behavioural support Youre familiar with WeightWatchers and trust the brand You find a points-based system helpful for accountability You want access to a large GLP-1 community and virtual workshops You prefer a well-known programme with 60+ years of heritage Frequently asked questions Can I get Mounjaro or Wegovy through WeightWatchers in the UK