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Water Retention (Transient) One of the most common side effects is mild water retention , which typically manifests as: Slight bloating Softness around joints Temporary weight gain due to increased extracellular water This is caused by: Increased GH and IGF-1 levels , which promote sodium retention and water shifts into tissues Water retention is typically: Mild and transient More noticeable at higher doses (300 mcg+) or when stacked with MK-677 (MK-677 (Ibutamoren) Cycle) Managing it: Keep sodium intake moderate Ensure proper hydration Adjust dosing if necessary Increased Appetite Because GHRP-2 binds to the ghrelin receptor , many users experience increased appetite which can be helpful or undesirable depending on your goals

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If you are new to high-fiber foods, increasing fiber too quickly can cause bloating or nausea

But the main issue comes from people using Ozempic for weight loss, instead of Wegovy

These results could lead to fresh pain relief options that skip addictive opioids or NSAIDs, which can harm the heart.