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Patients with a personal or family history of breast cancer should use choline supplementation cautiously, as some observational studies suggest high-dose choline intake correlates with increased breast cancer risk in genetically susceptible populations

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This review also emphasizes advancements in experimental models, including brain organoids and transgenic animals, which serve as crucial platforms for mechanistic studies and therapeutic validation

The mechanism of action of Rybelsus involves several complementary pathways

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Rupani, B., Caputo, F