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however, only variable efficacy has been demonstrated in reducing disease activity in SLE patients, possibly due to trial design that cannot preselect those patients that might benefit the most from peptide immunotherapy

10.1007/s10534-021-00296-y 200 PrajapatiM.ZhangJ

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Microdosing GLP-1 for autoimmune conditions is an emerging approach that some providers use to balance weight management with autoimmune disease management

Reduced NO levels also induce the expression of adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin, which mediate leukocyte recruitment to sites of endothelial injury (38)

But context matters more