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Weight loss plateau mechanisms appear to be primarily metabolic adaptation rather than receptor tolerance
doi: 10.2147/DDDT.S213910 75 YangMMaXXuanXDengHChenQYuanL
Gastrointestinal adverse effects, initially viewed as limiting, were ultimately managed through dose titration and formulation design
The manufacturers quickly discouraged and filed lawsuits against companies selling alternative versions of the drug with allegations of misleading advertising, unfair competition and deceiving patients
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