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The TC (Figure 6D) and TG (Figure 6E) contents in serum of rats in T2DM + RYGB and T2DM + EX-4 groups significantly reduced after surgery, while those in T2DM and T2DM + sham groups increased steadily

Hepat Mon 10:1216 Kim E, Viatour P (2020) Hepatocellular carcinoma: old friends and new tricks

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Given that alcohol and drug abuse activate the same reward pathways involved in food intake, it is plausible that appetite-regulating peptides, such as GLP-1, exert their effects on brain regions associated with reward and addiction [20, 21]

In the Wnt pathway, the key step of the Wnt pathway is the binding of the Wnt protein to the Frizzled receptor, and the nuclear redox protein (NRX) blocks Disheveled (DVL) and plays a negative regulatory role in the Wnt pathway (Yu et al., 2021)