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The specific deletion of IGF-1R from Treg cells abolished their ability to undergo IGF-1-induced proliferation and the therapeutic effects on experimental mouse encephalomyelitis

Long-Term Considerations While clinical trials up to 24 weeks demonstrate excellent safety, data on continuous use beyond 6-12 months remains limited

Nutrition 2014;30(9):1081-4

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Wu 2 Author information Abstract Subnormal levels of liver enzymes, below the lower limit of normal on local laboratory reports, can be useful diagnostically