Biohacker Dave Asprey highlights synergies: "Combining peptides with 5-Amino-1MQ creates buzz for NAD+ enhancement and metabolic optimization."[28] Dr
WEIGHT For those with deficiencies, B12 shots provide the potentially useful perk of increasing metabolism
Scientific References Hydroxocobalamin: a medicine to treat vitamin B12 deficiency
According to the NIH Office of Dietary Supplements, functional B12 deficiency is most commonly seen in patients with one or more of the following: Age over 50 stomach acid production declines with age, and stomach acid is required to free B12 from food PPI or H2 blocker use reflux medications suppress the acid needed for B12 absorption Metformin use, which interferes with B12 absorption directly Vegan or vegetarian diets B12 is found almost exclusively in animal products Gut conditions including celiac, IBS, SIBO, and Crohns MTHFR mutations that affect how B12 is metabolized once absorbed Heavy alcohol use The symptoms of low B12 are easy to dismiss: fatigue, brain fog, low mood, tingling in the hands or feet, weakness, and shortness of breath on mild exertion
Thiamine (Vitamin B1) Essential for energy generation, brain and nerve function, and cardiac muscle activity
doi:10.3945/ajcn.111.020230
