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Blocking the degradation of GLP-1 by inhibiting DPP-4 is how certain types of diabetes medicine work

Clinical trials demonstrate that discontinuation typically results in weight regain

For individuals taking glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity), or the dual GIP/GLP-1 receptor agonist tirzepatide (Mounjaro, Zepbound), maintaining adequate magnesium status may be particularly important

Endocrinology 2000;141:46005.ArticlePubMed 62

Drucker DJ, 2018