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References Gilbert MP, Bain SC, Franek E, et al

Meanwhile, GIP alone affects fat cells

Data extraction and risk of bias assessment Two researchers extracted data including the characteristics of the study population (number of patients per group, age, sex, diabetic status, liver disease status [NAFLD or NASH], and BMI per group), intervention(s) (TZD or GLP-1RA, treatment duration), control(s), outcome(s), and study results for each outcome according to a predefined Excel format

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The compounded versions of semaglutide may have other ingredients mixed in or may contain different forms of the active drug, which is not the same as the FDA-approved semaglutide products

Sugar-free gum throughout the day Chewing stimulates saliva production mechanically, independent of any ingredient effect