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Ispaghula is a bulk-forming soluble fibre supplement that works locally in the gut to relieve constipation and support regular bowel movements

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Mild stomach discomfort or cramping occurs in 2-4% of users

ZnT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles

Brand-name Ozempic accounted for nearly 40 per cent of that spending