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The amounts of L-carnitine, acetyl-L-carnitine, L-ARG and NAC that we used (only 500 mg, 250 mg, 500 mg and 50 mg, respectively) were lower than those previously reported to be effective in PCOS patients (12, 30-32)

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Furthermore, in our discussion, we highlighted the immense potential of spatial omics technologies in unraveling the molecular mechanisms of OA and in the development of novel therapeutic strategies, proposing future research directions and challenges