For an IT tear, ACL/MCL the patient would draw up 200mcg into an insulin syringe and inject as close to the tendon as possible twice per day, usually in the morning and evening time
But that peripheral-only action means it does not suppress appetite, does not change energy expenditure through central pathways, and does not produce the dramatic caloric deficits that GLP-1 agonists like semaglutide or tirzepatide create
Metabolic research focus: Examined in obese rodent studies for changes in weight gain patterns, fat oxidation, and markers associated with lipolysis and lipogenesis
Research indicates both topical and intraperitoneal administration routes produced similar wound healing effects in animal models
The authors reported significant reductions in total testosterone and free androgen index, accompanied by increases in SHBG and improved reproductive outcomes
This system rated cartilage structural integrity from 0, defined as normal to 6, defined as complete disorganization, and assessed cellularity from 0, defined as normal, to 3, defined as hypocellularity, for a total possible score of 0 to 9