Comparative analysis of antioxidant, anticholinesterase, and antibacterial activity of microbial chondroitin sulfate and commercial chondroitin sulfate
Regulatory pathways for biomarker approval should be clarified to facilitate clinical implementation of validated markers (May et al., 2010)
For the research context it is key for understanding why amylin analogs do not develop tolerance with chronic use (unlike many other anti-obesity molecules)
Whereas in vitro experiments showed that S375 is phosphorylated by GRK5 upon morphine exposure (Doll et al., 2012) and S375 phosphorylation plays a major role in MOR desensitization (Schulz et al., 2004), S375A knock-in mice still present anti-nociceptive tolerance upon acute and chronic exposure to morphine (Grecksch et al., 2011)
Cellular effects of pyocyanin, a secreted virulence factor of pseudomonas aeruginosa
Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span