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Additionally, a review of 12 studies found that supplementing with berberine led to significant reductions in body weight, body mass index, and belly fat

"The findings in our study reinforce that exercise cannot be optional for people taking these medications," he said

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"What's particularly encouraging is that the benefit appears to increase over time rather than fade, and that it behaves like a drug in terms of dose response," Dr Sullivan said, adding that the results give confidence "that we're targeting the right biology"

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This is a pre-filled injection format of LY3437943, a triple agonist binding GIP, GLP-1 and glucagon receptors currently in Phase 3 trials expected to conclude in May 2026 [6][8]