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The amount of oral intake needed to achieve gastric and intestinal fullness and signal satiety to the brain through the gut-brain axis can overwhelm the evolutionarily determined metabolic capacity of peripheral organs such as liver, pancreas, fat tissue, and muscles

Sep 2015;1(3):119-122

The combined effect can lead to an amplified anticoagulant effect, potentially pushing the patient beyond their therapeutic range and increasing the likelihood of hemorrhagic complications (242)

Jiang S, Cai J, Wallace DC, Jones DP

Some research suggests it may help maintain telomere length, which is associated with aging

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