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Additionally, studies have revealed that icariin and associated improvements in behavioral tests are accompanied by anti-inflammatory action, anti-oxidant action, Inhibited activation of NF-kB signaling, as well as a decrease in levels of SGK1 (serum and glucocorticoid-regulated kinase 1) and FKBP5 (FK506 binding protein 5) expression (Wei et al., 2016)

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doi: 10.3390/foods14101749 75 PachalSKumarHJainRGoelBKesharwaniSKesharwaniSSet al

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doi: 10.1095/biolreprod.112.102129 92 LiYHuangT-TCarlsonEJMelovSUrsellPCOlsonJLet al