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doi: 10.1207/s15327914nc5002_11 94 Saavedra-LeosMZJordan-AlejandreEPuente-RiveraJSilva-CzaresMB

However, while vitamin B12 supplements may help those with neurological function concerns or deficiencies, the evidence isnt strong enough to support its use as a standalone treatment for depression

The agency warns that compounded versions are not regulated as closely as generic and branded medicines

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For less urgent concerns, patients should contact their GP or rheumatology team promptly if they experience worsening joint symptoms, new swelling, or signs of infection, as these may require assessment and treatment adjustment