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Most side effects are mild and resolve on their own or can be managed by your healthcare provider

doi: 10.1016/j.nurt.2010.07.005

Mechanistically, hypervolaemia increases the haemodynamic workload to the filtration surface present, for example, causing glomerular hyperfiltration that imposes shear stress to the glomerular filtration barrier 86

Losing just 510% of body weight can significantly lower these risks

Prospective patients should review current FDA guidance on compounded GLP-1 availability and discuss risks, alternatives, and pharmacy sourcing with a licensed clinician before proceeding with any compounded option

Evaluate diet and activity patterns before considering dose increases