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(03:43): So you'd have efficient lowering of glucose through a dual mechanism with increasing insulin, lowering glucagon, and then it was safe because there wasn't this hypoglycemia you get from insulin

Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: a randomised, double-blind, placebo-controlled, clinical trial

Most adults receive between 0.2mg and 0.3mg daily, equivalent to roughly 3 micrograms per kilogram of body weight

Wang X, Li Y, He M, Kong X, Jiang P, Liu X

Tirzepatide acta como un agonista dual en el receptor similar al pptido glucagonoide tipo 1 (GLP-1R) y el receptor del polipptido insulinotrpico dependiente de glucosa (GIPR), ambos miembros de la familia GPCR de tipo secretina clase B