Given the natural fluctuations in hormone levels and the intricate rhythms of human physiology throughout the day and over a persons lifetime, there is concern about the uncertain health ramifications of sustained elevation of incretin activity over decades of treatment
In addition, the Baltimore Longitudinal Study of Aging, a long-term follow-up study of an adult caucasian population, showed that IGT, and not impaired fasting glucose tolerance, elevates the risk of coronary heart disease [8]
This also increases the risk of overdosing
Small bubbles are normal
And, a small proof-of-concept study found they improved nausea for people on GLP-1s within 520 minutes
both these factors may improve brain health and explain the reduced risk of conditions like Alzheimers disease and dementia. While GLP-1RA drugs display effectiveness against a wide array of health problems, the magnitude of associated benefits is modest about a 10 percent to 20 percent reduction for most outcomes