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Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7), a Phase 3b trial of semaglutide, demonstrated that semaglutide was superior to dulaglutide in improving glycemic control and weight loss 10

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Studies have shown that peroxynitrite generated by the coordinated action of inducible nitric oxide synthase (iNOS) and NOX1 effectively suppresses excessive proliferation of ileal bacteria, preventing the reflux of colonic microbiota [116]

Brzezinski A, Vangel MG, Wurtman RJ, Norrie G, Zhdanova I, Ben-Shushan A, et al

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A new study found that over time, the majority of weight loss from GLP-1 medication was from fat loss, and not muscle loss