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2005;90(2):611-614.doi:10.1210/jc.2004-1719 11

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In the coupling reaction, the iodinated tyrosine residues are combined by TPO to make triiodothyronine (T3) and tetraiodothyronine (T4), where MIT and DIT join to form T3, and two DIT molecules form T4

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You may notice a smooth tongue and have gut-related issues like bloating, diarrhea, loss of appetite, and passing gas