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Proc Natl Acad Sci U S A 105:1356813573 Shibata T, Kokubu A, Saito S, Narisawa-Saito M, Sasaki H, Aoyagi K, Yoshimatsu Y, Tachimori Y, Kushima R, Kiyono T, Yamamoto M (2011) NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer
Additionally, we and others have observed that other lipoyl adducts can be formed when lipid peroxidation products accumulate or following nitrosylation during macrophage activation 15,16,17,18
Vitamin B12 is the "generic descriptor" name for any of such vitamers of vitamin B12
Some researchers even drop back to the previous dose temporarily before trying the increase again
That sounds fairly straightforward
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