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Efficacy also showed a modest reduction with age: each additional 10 years of age corresponded to a 0.5% reduction in BMI change (around 0.45 kg reduced weight loss efficacy), which is directionally consistent with recent clinical trial meta-analyses 12,13

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Weight loss drugs are expensive and are covered by some insurance plans, but most people get insurance through their employers, so its a question of whether employers opted in or out of weight loss benefits, says Michelle Pearlman, MD, CEO and co-founder of Prime Institute and ByteMD and a physician who is board-certified in internal medicine, gastroenterology, and obesity medicine