Kava may also be used as an herbal remedy, where it is currently regulated by the Dietary Supplements Regulations
It exacerbates acute kidney injury (AKI) by altering gut microbiota and increasing the gut-derived metabolite 3-indoleacrylic acid, which activates neutrophils to release neutrophilic granule protein (NGP), causing renal damage (Dong et al., 2025)
Complex tissue injuries often require coordinated responsesinflammatory control, cellular migration, angiogenesis, and matrix remodelingmaking multi-component approaches relevant for studying comprehensive repair strategies
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Given the known role of Y1-R in GLP-1R-mediated regulation of insulin secretion, we were surprised to find that Y1-R also stimulated glucose uptake in muscle via a mechanism that was fully independent of insulin stimulation
By gently attenuating muscular contraction, it provides a non-invasive, lower-risk alternative to botulinum toxin