True needle phobia is a real medical condition
Clinically abandoned due to a rat carcinogenic signal (long-term hepatocarcinomas)
Tricyclic Antidepressants (TCAs) and Monoamine Oxidase Inhibitors (MAOIs), though less commonly used as first-line treatments due to their broader side effect profiles, remain effective for treatment-resistant cases and specific mood disorders
But until now, there hasnt been any data from large epidemiologic studies. Results showed use of GLP-1 agonists compared with bupropion-naltrexone correlated with a 9.09 (95% CI, 1.25-66), 4.22 (95% CI, 1.02-17.4) and 3.67 (95% CI, 1.15-11.9) times higher risk for pancreatitis, bowel obstruction and gastroparesis, respectively
Special populations : Pregnant, lactating, or severely hepatorenal patients should consult a physician
A.Yousefi-ManeshH.EslamiyehM.VafaeiA.ForoutaniL.et al (2020)