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Recent progress in genome sequencing and comparative genomics indicates several housekeeping gene products, that likely are essential for the pathogen viability but have no homologs in humans

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Mol Neurobiol 53:50255029 Deuschl G, Schade-Brittinger C, Krack P, Volkmann J, Schfer H, Btzel K, Daniels C, Deutschlnder A, Dillmann U, Eisner W, Gruber D, Hamel W, Herzog J, Hilker R, Klebe S, Kloss M, Koy J, Krause M, Kupsch A, Lorenz D, Lorenzl S, Mehdorn HM, Moringlane JR, Oertel W, Pinsker MO, Reichmann H, Reuss A, Schneider GH, Schnitzler A, Steude U, Sturm V, Timmermann L, Tronnier V, Trottenberg T, Wojtecki L, Wolf E, Poewe W, Voges J, German Parkinson Study Group, Neurostimulation Section (2006) A randomized trial of deep-brain stimulation for Parkinsons disease