These detrimental molecules promote inflammation, fibrosis, and tissue damage
Supporting Liver Detoxification: It plays a crucial role in capturing and eliminating toxins from the liver, preventing conditions like fatty liver disease
TERN is also initiating IND-enabling activities in 2023 for TERN-800, an oral GIPR modulator , with the intention of being used in combination with GLP1R agonists
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490 Furthermore, Sir2 , as a mammalian homolog of SIRT1, is the downstream effector of increased Nmnat activity, which can lead to axon protection in Wallerian degeneration slow mice
