The Journal of Clinical Endocrinology & Metabolism
Compound identity at a glance Name: Retatrutide INN: LY3437943 Class: Triple incretin receptor agonist Structure: 39-amino-acid synthetic peptide Dosing interval: Once weekly (research protocols) Developer: Eli Lilly For the full molecular reference (molecular formula, molecular weight, CAS number and the 39-amino-acid sequence) see the Retatrutide molecular profile
The rapid elevation in reverse T3 that occurs with calorie-restricted diets may be an early warning that metabolic damage is occurring which will result in regaining any weight that is lost
2016;113(19):E2655E2664
The platforms stated current offerings include: Injectable GLP-1s: Compounded semaglutide (injectable), Wegovy, Ozempic, Zepbound, Mounjaro, and generic liraglutide, available for eligible patients depending on state and current supply Following the March 2026 Novo Nordisk deal, access to branded Ozempic is now part of the platform Oral Medication Kits: Personalized oral kits combining medications such as bupropion/naltrexone, metformin, and topiramate, targeting food noise, slow metabolism, and appetite regulation without injections App and Support: 360 care, including nutritional principles, behavioral programs, and custom lessons in the Hims app
The usual dose of acarbose is 50100 mg three times a day with meals