Editor information Editors and Affiliations Rights and permissions Copyright information 2017 Springer International Publishing AG About this entry Cite this entry Stoopler, E.T., Alawi, F
Despite their origins in diabetes management, GLP-1 agonists are now widely used for weight loss in non-diabetic individuals and have been approved for this purpose by the FDA
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Sitagliptin (Aschner et al., 2006), saxagliptin (Rosenstock et al., 2009), and vildagliptin (Keating, 2010) all improve glucose metabolism in diabetic patients
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Based on these researches, clinical trials targeting HO-1 should be carried out to evaluate its application in the treatment of DN, so as to provide evidence for clinical application