However, when combined with GLP-1 activation, the opposite effect occurred
For the serum lipid, although only 5 trials provided sufficient data, the improvements in semaglutide group were still observed both on total cholesterol (WMD -030, 95% CI -052 to -008
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Study: Semaglutide cardiovascular outcomes align more closely with attained dose than achieved weight loss
These were mostly mild or moderate, and all administration-site reactions were non-serious