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Figure 6 3.8 CB-839 did not improve cytotoxicity in combination with venetoclax, AZD-5991, and ibrutinib in primary CLL lymphocytes We then tested these drug combinations in the primary CLL cells, both in the native condition ( Figure 7A ) and in media supplemented with cytokines (CD40 ligand and interleukin-4) to mimic the microenvironment and maintain viability ( Figure 7B )

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Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

FIGURE 6 Collectively, these data provide compelling evidence that GO@GSH-FA effectively mitigates the inflammatory response induced by OGD/R, as indicated by the marked reduction in the expression of key proinflammatory markers

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