The enzyme tyrosinase mediates the manufacturing of melanin
One major limitation is the lack of standardized in vivo models and clinically relevant endpoints to assess barrier function, which impedes the translation of preclinical findings into therapeutic or preventive strategies
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Epithelial solid tumors (~40%), e.g.: Hepatocellular carcinoma
This active ingredient is now being used in skin-brightening products because it can stop tyrosinase activity and lower melanin production more effectively than other glutathione forms
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