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Most people see additional weight loss resume within 4-8 weeks of switching

And not only that but TRIUMPH-1 was extended to 104 weeks for a subset of patients that were still losing weight at week 80

In the end, the question is not simply whether metformin should be stopped, but rather: Which patient, at what stage, and under what conditions might patients still benefit from metformin continuation

Thus in addition to increasing GLP-1 concentration, recent research shows that it also lowers insulin concentration and stabilizes ghrelin levels

While continuous treatment is ideal, wed rather you get some benefit than none

You may experience some gastrointestinal symptoms (increased gas, bloating, nausea, or loose stools) that usually resolve over the initial 14 days or with discontinuation of the product